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Welcome to the He Group!



He Lab breakthrough has major implications in basic biology UChicago News


Dr. Diana West-Szymanski, from the He Lab, as one of the '40 under 40 scientists, leaders of next generation of translational research Halo Awards


Dr. Chuan He to receive the 2019 ACS Chemical Biology Lectureship Award ACS Award


Visit Center for Dynamic RNA Epitranscriptomes (CEGS-CDRE) website CDRE


Prof. Chuan He to lead Chicago’s first Center of Excellence in Genomic Science (CEGS) More...


Recent Publications:

Han, D.*; Liu.; J.; Chen, C.; Dong, L.; Liu, Y.; Chang, R.; Huang, X.; Liu, Y.; Wang, J.; Dougherty, U.; Bissonnette, M. B.; Shen, B.; Weichselbaum, R. R.; Xu, M. M.*; He C.*. Anti-tumour immunity controlled through mRNA m6A methylation and YTHDF1 in dendritic cells. Nature 2019, 566, 270-274. [pdf]

Shi, H.; Zhang, X.; Weng, Y. L.; Lu, Z.; Liu, Y.; Lu, Z.; Li, J.; Hao, P.; Zhang, Y.; Zhang, F.; Wu, Y.; Delgado, J. Y.; Su, Y.; Patel, M. J.; Cao, X.; Shen, B.; Huang, X.; Ming, G. L.; Zhuang, X.; Song, H.*; He, C.*; Zhou, T.* m6A facilitates hippocampus-dependent learning and memory through Ythdf1. Nature 2018, 563, 240-253.[pdf]

Frye, M.*; Harada, B. T.; Behm, M.; He, C.*. RNA modifications modulate gene expression during development. Science 2018, 361, 1346-1349. [pdf]