Research Highlights
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Welcome to the He group!

Recent Publications:

Wang, X.; Zhao, B. S.; Roundtree, I. A.; Lu, Z.; Han, D.; Ma, H.; Weng, X.; Chen, K.; Shi, H.; He, C. N6-methyladenosine Modulates Messenger RNA Translation Efficiency. Cell 2015, 161, 1388-1399. [pdf]

Greer, E. L.; Blanco, M. A.; Gu, L.; Sendinc, E.; Liu, J.; Aristizábal-Corrales, D.; Hsu, C. H.; Aravind, L.; He, C.; Shi, Y. DNA Methylation on N6-Adenine in C. elegans. Cell 2015, 161, 868-878. [pdf]

Fu, Y.; Luo, G. Z.; Chen, K.; Deng, X.; Yu, M.; Han, D.; Hao, Z.; Liu, J.; Lu, X.; Doré, L. C.; Weng, X.; Ji, Q.; Mets, L.; He, C. N6-methyldeoxyadenosine marks active transcription start sites in chlamydomonas. Cell 2015, 161, 879-892. [pdf]

Zhang, G.; Huang, H.; Liu, D.; Cheng, Y.; Liu, X.; Zhang, W.; Yin, R.; Zhang, D.; Zhang, P.; Liu, J.; Li, C.; Liu, B.; Luo, Y.; Zhu, Y.; Zhang, N.; He, S.; He, C.; Wang, H.; Chen, D. N6-methyladenine DNA modification in Drosophila. Cell 2015, 161, 893-906. [pdf]

Luo, G. Z.; MacQueen, A.; Zheng, G.; Duan, H.; Dore, L. C.; Lu, Z.; Liu, J.; Chen, K.; Jia, G.; Bergelson, J.; He, C. Unique features of the m(6)A methylome in Arabidopsis thaliana. Nat. Commun. 2014, 5, 5630. [pdf]

Fu, Y.; Dominissini, D.; Rechavi, G.; He, C. Gene expression regulation mediated through reversible m(6)A RNA methylation. Nat. Rev. Genet. 2014, 15, 293-306. [pdf]

Zhou, L.; Bosscher, M.; Zhang, C.; Ozcubukcu, S.; Zhang, L.; Zhang, W.; Li, C. J.; Liu, J.; Jensen, M. P.; Lai, L.; He, C. A protein engineered to bind uranyl selectively and with femtomolar affinity. Nat. Chem. 2014, 6, 236-241. [pdf][news][news]

Wang, X.; Lu, Z.; Gomez, A.; Hon, G. C.; Yue, Y.; Han, D.; Fu, Y.; Parisien, M.; Dai, Q.; Jia, G.; Ren, B.; Pan, T.; He, C. N6-methyladenosine-dependent regulation of messenger RNA stability.Nature. 2014, 505, 117-120. [pdf] [news]


Dr. Dan Dominissini has been selected as one of the four young scientists winning Science and SciLifeLab category award! [news] He was invited by Science to accept the award and to participate in part of Nobel Price activities. [picture] Assay published in Science [link]