Research Highlights
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Welcome to the He Group!


Chuan He honored for contributions to advancing cancer research U Chicago   MSK Cancer Center


RNA Society/Scaringe Graduate Student Award for Boxuan Zhao, He Group lab member More...


An epigenetics gold rush: new controls for gene expression More...


Epitranscriptome analysis is Method of the Year 2016 (Nature Methods) More...


Visit Center for Dynamic RNA Epitranscriptomes (CEGS-CDRE) website CDRE


Prof. Chuan He to lead Chicago’s first Center of Excellence in Genomic Science (CEGS) More...


Recent Publications:

Su, R.; Dong, L.; Li, C.; Nachtergaele, S.; Wunderlich, M.; Qing, Y.; Deng, X.; Wang, Y.; Weng, X.; Hu, C.; Yu, M.; Skibbe, J.; Dai, Q.; Zou, D.; Wu, T.; Yu, K.; Weng, H.; Huang, H.; Ferchen, K.; Qin, X.; Zhang, B.; Qi, J.; Sasaki, A. T.; Plas, D. R.; Bradner, J. E.; Wei, M.; Marcucci, G.; Jiang, X.; Mulloy, J. C.; Jin, J.*; He, C.*; Chen, J.*. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell 2018, 172, 1-16. [pdf]

Zhao B.S.; Wang X.; Beadell A.V.; Lu Z.; Shi H.; Kuuspalu A.; Ho R.K.; He C. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature 2017, 542, 475-478.[pdf]

Roundtree, I. A.; Evans, M. E.; Pan, T.*; He, C.*. Dynamic RNA Modifications in Gene Expression Regulation. Cell 2017, 169, 1187-1200. [pdf]